Hi Dr. Lamm,
My husband has high grade bladder cancer and I would like to know how long the side effects of BCG such as weakness and fatigue can last?
-Marlene
Dear Friend,
Fatigue and malaise, similar to that we sometimes feel after a vaccination, occurs in about one in five patients receiving BCG. Like most of the side effects, it is more common beginning after the second or third instillation. Fever can also occur, and we consider low grade, mild fever and tiredness to be a sign that a good immune response is occurring. Studies have found that those who develop fever have a lower risk of tumor recurrence. Generally the symptoms last for two or three days, and gradually resolve. If your husband is still very fatigued when it is time to get the next treatment, we would consider delaying the treatment and reducing the dose.
Best regards,
Don Lamm, MD
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